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Antiglucocorticoid therapy for older adults with anxiety and co‐occurring cognitive dysfunction: results from a pilot study with mifepristone

Identifieur interne : 004C27 ( Main/Exploration ); précédent : 004C26; suivant : 004C28

Antiglucocorticoid therapy for older adults with anxiety and co‐occurring cognitive dysfunction: results from a pilot study with mifepristone

Auteurs : Eric J. Lenze [États-Unis] ; Tamara Hershey [États-Unis] ; John W. Newcomer [États-Unis] ; Jordan F. Karp [États-Unis] ; Daniel Blumberger [Canada] ; Jennifer Anger [États-Unis] ; Peter Doré [États-Unis] ; David Dixon [États-Unis]

Source :

RBID : ISTEX:541A67ECCE44FAEF955C2D500EBC0E9DA9961AC3

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English descriptors

Abstract

In older adults with anxiety disorders, chronically elevated cortisol may contribute to cognitive impairment and elevated anxiety. We conducted a pilot study with mifepristone, a glucocorticoid receptor antagonist, as a potential treatment for late‐life anxiety disorders and co‐occurring cognitive dysfunction.

Url:
DOI: 10.1002/gps.4085


Affiliations:


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